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Rehabilitation from musculoskeletal injuries focuses on reestablishing and monitoring muscle activation patterns to accurately produce force. The aim of this study is to explore the use of a novel low-powered wearable distributed Simultaneous Musculoskeletal Assessment with Real-Time Ultrasound (SMART-US) device to predict force during an isometric squat task. Participants (N = 5) performed maximum isometric squats under two medical imaging techniques; clinical musculoskeletal motion mode (m-mode) ultrasound on the dominant vastus lateralis and SMART-US sensors placed on the rectus femoris, vastus lateralis, medial hamstring, and vastus medialis. Ultrasound features were extracted, and a linear ridge regression model was used to predict ground reaction force. The performance of ultrasound features to predict measured force was tested using either the Clinical M-mode, SMART-US sensors on the vastus lateralis (SMART-US: VL), rectus femoris (SMART-US: RF), medial hamstring (SMART-US: MH), and vastus medialis (SMART-US: VMO) or utilized all four SMART-US sensors (Distributed SMART-US). Model training showed that the Clinical M-mode and the Distributed SMART-US model were both significantly different from the SMART-US: VL, SMART-US: MH, SMART-US: RF, and SMART-US: VMO models (p < 0.05). Model validation showed that the Distributed SMART-US model had an R2 of 0.80 ± 0.04 and was significantly different from SMART-US: VL but not from the Clinical M-mode model. In conclusion, a novel wearable distributed SMART-US system can predict ground reaction force using machine learning, demonstrating the feasibility of wearable ultrasound imaging for ground reaction force estimation.more » « less
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Understanding the petrological and geochemical processes shaping the Moho transition zone (MTZ) is crucial for advancing our knowledge of thermal and chemical exchanges between the oceanic crust and the residual upper mantle. In this study, we systematically investigate the MTZ outcropped within the Zedong ophiolite, located in the eastern part of the Yarlung-Tsangpo Suture Zone (YTSZ), with the aim of at reconstructing the magmatic processes responsible for generating the petrological Moho. The Zedong MTZ comprises a sequence of dunite, wehrlite, pyroxenite, and gabbro, with frequent occurrences of clinopyroxene-rich lithologies. Cyclicity within the MTZ sequences is characterized by the recurrence of olivine-rich intervals and the presence of zig-zag patterns in both major and trace elements of clinopyroxenes. Zircon Usingle bondPb dating on the Zedong gabbros supports the coeval formation of the Zedong ophiolite with other YTSZ ophiolites. Clinopyroxene in the Zedong MTZ follows a differentiation sequence characterized by an increase in contents of Al2O3 and TiO2, coupled with a decrease in Mg#. This differentiation sequence along with frequent occurrences of amphibole suggest the evolution of a primitive hydrous melt depleted in Al2O3, TiO2, and Na2O. The depleted Ndsingle bondHf isotopes and rare earth element patterns of the MTZ rocks indicate that their parental magmas originated from fluid-enhanced re-melting of a previously depleted mantle. Additionally, we proposed that the initiation of a new subduction zone results in the re-melting of the mantle peridotite, leading to the formation of primitive hydrous basaltic melts. The variable lithologies observed in the Zedong MTZ arise from fractional crystallization and repeated replenishment of hydrous melts.more » « less
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Exotic structures with interesting physical and chemical properties can be achieved by self-organizing engineered building blocks. The central aim for self-assembly is to precisely control the position and orientation of individual building blocks. In this work, we use topological defects (disclinations) in nematic liquid crystals as templates to direct the self-assembly of colloidal particles into designable 3D structures. By photopatterning preprogrammed molecular orientations at two confining surfaces, we created pre-designable disclination networks and characterized their interactions with spherical colloidal particles. We find that colloidal particles are attracted to different disclinations depending on the orientation of the point defect (elastic dipole) around the colloids. We demonstrate that the positions, network structures, and orientation of the elastic dipoles of the colloidal chains can be pre-designed and reconfigured with remote illumination of polarized light.more » « less
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Disclinations in nematic liquid crystals are of great interest both theoretically and practically. The ability to create and reconfigure disclinations connecting predetermined points on substrates could enable novel applications such as directed self-assembly of micro/nanoparticles and molecules. In this study, we present a novel approach to design and create disclination interconnects that connect predetermined positions on substrates. We demonstrate that these interconnects can be switched between different states by re-writing photoalignment materials with linearly polarized light, and can be switched between degenerate states using electric fields. The demonstrated strategy allows for creation of multi-scale designer disclination networks and promises potential applications in directed assembly of colloidal micro-/nano-particles, command of active matter, and liquid crystal microfluidicsmore » « less
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Abstract Pyroxenite veins and dikes are commonly observed in the mantle section of ophiolites. Because of their mantle occurrence, these pyroxenites are free from crustal contamination and offer a unique opportunity for studying mantle compositions and melt–rock interaction processes. We conducted an integrated petrological and geochemical study of a suite of composite orthopyroxenite, websterite, and pyroxene-bearing dunite veins from the Xiugugabu ophiolite located on the western segment of Yarlung–Zangbo Suture Zone. The dunite is separated from the host peridotite by a layer of pyroxenite, forming a composite vein system. Systematic variations in major, minor, and trace element compositions in minerals across the composite veins are observed. Two generations of orthopyroxenes in the pyroxenites are characterized by high Mg#, low TiO2 concentrations, and depleted patterns of incompatible trace elements. Clinopyroxenes in the pyroxenites are characterized by high Mg#, low contents of TiO2 and Na2O, spooned shaped REE patterns, and a negative Zr anomaly. Through major and trace element modeling, we showed that both orthopyroxene and clinopyroxene were in equilibrium with melts with different compositions. This hypothesis is further confirmed by distinct initial Nd and Hf isotope ratios in the two pyroxenes. A model for the formation of composite pyroxenite veins is developed, whereby hydrous and silica-rich melts percolate along the margins of a dunite channel. The orthopyroxenite was formed by the reaction between a hydrous, silica-rich melt and the surrounding peridotite. The websterite is formed by reactive crystallization of a hybrid melt produced by mixing silica-rich melt and the melt formed by remelting of previously depleted peridotite in the deeper part of the mantle column. The extremely enriched Nd–Hf isotope compositions of the pyroxenite veins (εNd = −20.3 to +11.5 and εHf = −13.2 to +25.3, 125 million years ago) can be explained by the addition of ancient, recycled sediments to the mantle source in a supra-subduction setting. Based on the low-Cr# spinel in the Xiugugabu dunites (Cr# = 19–50) and the depleted nature of the parental melt of the Xiugugabu pyroxenites, we deduced that the formation of pyroxenites postdate the formation of the Xiugugabu ophiolite at ~125–130 Ma. Collectively, results from this study have provided support to the hypothesis that the Xiugugabu ophiolite experience a two-stage evolution, i.e., firstly formed in a mid-ocean ridge setting and subsequently modified in a supra subduction zone.more » « less
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Abstract The architecture of lower oceanic crust at slow- and ultraslow-spreading ridge is diverse, yet the mechanisms that produce this diversity are not well understood. Particularly, the 660-km2 gabbroic massif at Atlantis Bank (Southwest Indian Ridge) exhibits significant compositional zonation, representing a high magma supply end member for accretion of the lower ocean crust at slow and ultraslow-spreading ridges. We present the petrographic and geochemical data of olivine gabbros from the 809-meter IODP Hole U1473A at Atlantis Bank gabbroic massif. Structurally, the upper portion of U1473A consists of a ∼600-meter shear zone; below this, the hole is relatively undeformed, with several minor shear zones. Olivine gabbros away from the shear zones have mineral trace element compositions indicative of high-temperature reaction with an oxide-undersaturated melt. By contrast, olivine gabbros within shear zones display petrographic and chemical features indicative of reaction with a relatively low-temperature, oxide-saturated melt. These features indicate an early stage of primitive to moderately evolved melt migration, followed by deformation-driven transport of highly evolved Fe-Ti-rich melts to high levels in this gabbroic massif. The close relationship between shear zones and the reaction with oxide-saturated melts suggests that syn-magmatic shear zones provide a conduit for late-stage, Fe-Ti-rich melt transport through Atlantis Bank lower crust. This process is critical to generate the compositional zonation observed. Thus, the degree of syn-magmatic deformation, which is fundamentally related to magma supply, plays a dominant role in developing the diversity of lower ocean crust observed at slow- and ultraslow-spreading ridges.more » « less
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Eukaryotic cells in living tissues form dynamic patterns with spatially varying orientational order that affects important physiological processes such as apoptosis and cell migration. The challenge is how to impart a predesigned map of orientational order onto a growing tissue. Here, we demonstrate an approach to produce cell monolayers of human dermal fibroblasts with predesigned orientational patterns and topological defects using a photoaligned liquid crystal elastomer (LCE) that swells anisotropically in an aqueous medium. The patterns inscribed into the LCE are replicated by the tissue monolayer and cause a strong spatial variation of cells phenotype, their surface density, and number density fluctuations. Unbinding dynamics of defect pairs intrinsic to active matter is suppressed by anisotropic surface anchoring allowing the estimation of the elastic characteristics of the tissues. The demonstrated patterned LCE approach has potential to control the collective behavior of cells in living tissues, cell differentiation, and tissue morphogenesis.more » « less
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Liquid crystal elastomers (LCEs) hold a major promise as a versatile material platform for smart soft coatings since their orientational order can be predesigned to program a desired dynamic profile. In this work, we introduce temperature-responsive dynamic coatings based on LCEs with arrays of singular defects-disclinations that run parallel to the surface. The disclinations form in response to antagonistic patterns of the molecular orientation at the top and bottom surfaces, imposed by the plasmonic mask photoalignment. Upon heating, an initially flat LCE coating develops linear microchannels located above each disclination. The stimulus that causes a non-flat profile of LCE coatings upon heating is the activation force induced by the gradients of molecular orientation around disclinations. To describe the formation of microchannels and their thermal response, we adopt a Frank–Oseen model of disclinations in a patterned director field and propose a linear elasticity theory to connect the complex spatially varying molecular orientation to the displacements of the LCE. The thermo-responsive surface profiles predicted by the theory and by the finite element modeling are in good agreement with the experimental data; in particular, higher gradients of molecular orientation produce a stronger modulation of the coating profile. The elastic theory and the finite element simulations allow us to estimate the material parameter that characterizes the elastomer coating's response to the thermal activation. The disclination-containing LCEs show potential as soft dynamic coatings with a predesigned responsive surface profile.more » « less
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